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There are several matches for 'ATP-dependent metalloprotease'.
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4420 matches
showing page 1 of 221
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organism
protein
1)
Homo sapiens
YME1L1 -
ATP
-
dependent
zinc
metalloprotease
YME1L1;
ATP
-
dependent
metalloprotease
that catalyzes the degradation of folded and unfolded proteins with a suitable degron sequence in the mitochondrial intermembrane region. Plays an important role in regulating mitochondrial morphology and function by cleaving OPA1 at position S2, giving rise to a form of OPA1 that promotes maintenance of normal mitochondrial structure and mitochondrial protein metabolism. Ensures cell proliferation, maintains normal cristae morphology and complex I respiration activity, promotes antiapoptotic activity and protects [...]
[a.k.a. Q96TA2, NM_014263.4, YME1L1-207,
ATP-dependent metalloprotease
]
2)
Mus musculus
Yme1l1 -
ATP
-
dependent
zinc
metalloprotease
YME1L1;
ATP
-
dependent
metalloprotease
that catalyzes the degradation of folded and unfolded proteins with a suitable degron sequence in the mitochondrial intermembrane region (By similarity). Plays an important role in regulating mitochondrial morphology and function by cleaving OPA1 at position S2, giving rise to a form of OPA1 that promotes maintenance of normal mitochondrial structure. Ensures cell proliferation, maintains normal cristae morphology and complex I respiration activity, promotes antiapoptotic activity and protects mitochondria from th [...]
[a.k.a. Yme1l1-202, YME1-like 1 (S. cerevisiae), NP_038799.1,
ATP-dependent metalloprotease
]
3)
Drosophila melanogaster
YME1L -
ATP
-
dependent
zinc
metalloprotease
YME1L;
ATP
-
dependent
metalloprotease
that catalyzes the degradation of folded and unfolded proteins with a suitable degron sequence in the mitochondrial intermembrane region. Plays an important role in regulating mitochondrial morphology and function by cleaving Opa1, giving rise to a form of Opa1 that promotes maintenance of normal mitochondrial structure and mitochondrial protein metabolism. Ensures cell proliferation, maintains normal cristae morphology and complex I respiration activity, promotes antiapoptotic activity and protects mitochondria fr [...]
[a.k.a. FBgn0034792, YME1L-PD, YME1L-PC,
ATP-dependent metalloprotease
]
4)
Caenorhabditis elegans
ymel-1 -
ATP
-
dependent
zinc
metalloprotease
YME1 homolog;
ATP
-
dependent
metalloprotease
that catalyzes the degradation of folded and unfolded proteins with a suitable degron sequence in the mitochondrial intermembrane region (By similarity). Plays an important role in regulating mitochondrial morphology and function (By similarity); In the C-terminal section; belongs to the peptidase M41 family.
[a.k.a. M03C11.5, WBGene00010842, CAA88955.2,
ATP-dependent metalloprotease
]
5)
Saccharomyces cerevisiae
YME1 - Catalytic subunit of i-AAA protease complex; complex is located in mitochondrial inner membrane; responsible for degradation of unfolded or misfolded mitochondrial gene products; serves as nonconventional translocation motor to pull PNPase into intermembrane space; also has role in intermembrane space protein folding; mutation causes elevated rate of mitochondrial turnover; human homolog YME1L1 can complement yeast null mutant; In the C-terminal section; belongs to the peptidase M41 family.
[a.k.a. YPR024W, 2MV3, Tat-binding homolog 11,
ATP-dependent metalloprotease
]
6)
Homo sapiens
SPG7 - Paraplegin;
ATP
-
dependent
zinc
metalloprotease
. Plays a role in the formation and regulation of the mitochondrial permeability transition pore (mPTP) and its proteolytic activity is dispensable for this function ; In the N-terminal section; belongs to the AAA ATPase family.
[a.k.a. SPG5C, ENST00000644061, ENST00000645742.1]
7)
Homo sapiens
PSMD14 - 26S proteasome non-ATPase regulatory subunit 14; Component of the 26S proteasome, a multiprotein complex involved in the
ATP
-
dependent
degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. The PSMD14 subunit is a
metalloprotease
that specifically cle [...]
[a.k.a. R-HSA-2555396, R-HSA-174084, 6MSD]
8)
Mus musculus
Spg7 - Paraplegin;
ATP
-
dependent
zinc
metalloprotease
. Plays a role in the formation and regulation of the mitochondrial permeability transition pore (mPTP) and its proteolytic activity is dispensable for this function (By similarity); In the C-terminal section; belongs to the peptidase M41 family.
[a.k.a. Spg7-211, ENSMUSP00000119017, ENSMUST00000153285.8]
9)
Mus musculus
Psmd14 - 26S proteasome non-ATPase regulatory subunit 14; Component of the 26S proteasome, a multiprotein complex involved in the
ATP
-
dependent
degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. The PSMD14 subunit is a
metalloprotease
that specifically cle [...]
[a.k.a. R-MMU-453274, R-MMU-453279, R-MMU-1280218]
10)
Drosophila melanogaster
Rpn11 - 26S proteasome non-ATPase regulatory subunit 14;
Metalloprotease
component of the 26S proteasome that specifically cleaves 'Lys-63'-linked polyubiquitin chains. The 26S proteasome is involved in the
ATP
-
dependent
degradation of ubiquitinated proteins. The function of the 'Lys-63'-specific deubiquitination of the proteasome is unclear (By similarity). Belongs to the peptidase M67A family. PSMD14 subfamily.
[a.k.a. FBgn0028694, Rpn11-PA, UPI000007DDBE]
11)
Caenorhabditis elegans
spg-7 - AFG3-like protein spg-7; Acts as a component of the m-AAA protease complex which is an
ATP
-
dependent
metalloprotease
mediating degradation of non-assembled mitochondrial inner membrane proteins (By similarity). The complex is necessary for the assembly of mitochondrial respiratory chain and ATPase complexes (By similarity). Functions both in post-translational assembly and in the turnover of mistranslated or misfolded polypeptides. Plays a role in male tail tip morphogenesis. In the C-terminal section; belongs to the peptidase M41 family.
[a.k.a. Y47G6A.10, AFG3_CAEEL, NP_491165]
12)
Caenorhabditis elegans
rpn-11 - 26S proteasome non-ATPase regulatory subunit 14;
Metalloprotease
component of the 26S proteasome that specifically cleaves 'Lys-63'-linked polyubiquitin chains. The 26S proteasome is involved in the
ATP
-
dependent
degradation of ubiquitinated proteins. The function of the 'Lys-63'-specific deubiquitination of the proteasome is unclear (By similarity).
[a.k.a. K07D4.3, K07D4.3.1, UPI000007982E]
13)
Acidihalobacter ferrooxidans
hflB -
ATP
-
dependent
metalloprotease
; Acts as a processive,
ATP
-
dependent
zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
[a.k.a. BW247_12870, APZ43870.1, A0A1P8UJ81,
ATP-dependent metalloprotease
]
14)
Acidihalobacter prosperus
hflB -
ATP
-
dependent
metalloprotease
; Acts as a processive,
ATP
-
dependent
zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
[a.k.a. BJI67_09855, AOV17326.1, ftsH,
ATP-dependent metalloprotease
]
15)
Acidithiobacillus thiooxidans
ftsH_2 -
ATP
-
dependent
zinc
metalloprotease
FtsH; Acts as a processive,
ATP
-
dependent
zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
[a.k.a. GCA_002079865_00615, ftsH, ATP-dependent zinc metalloprotease FtsH,
ATP-dependent metalloprotease
]
16)
Acinetobacter sp. HR7
ftsH -
ATP
-
dependent
metalloprotease
; Acts as a processive,
ATP
-
dependent
zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
[a.k.a. GW12_05050, KGT48473.1,
ATP-dependent metalloprotease
]
17)
Acromyrmex echinatior
G5I_03989 - Protein YME1-like protein.
[a.k.a.
ATP-dependent metalloprotease
, EC 3.4.24.-, Protein YME1-like protein]
18)
Actinobacillus equuli
hflB - Inner membrane metalloprotease; may be involved in degradation of aberrant cytoplasmic and membrane proteins; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AAA ATPase family.
[a.k.a. ACEE_04155, AIZ78974.1,
ATP-dependent metalloprotease
]
19)
Acyrthosiphon pisum
J9KB37_ACYPI - AAA domain-containing protein.
[a.k.a. 100169567,
ATP-dependent metalloprotease
, J9KB37]
20)
Adlercreutzia equolifaciens
hflB -
ATP
-
dependent
metalloprotease
; Acts as a processive,
ATP
-
dependent
zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
[a.k.a. BAN77597.1, AEQU_1628,
ATP-dependent metalloprotease
]
4420 matches
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